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| 心梗三合一联合检测在心肌梗死诊断中的作用
摘 要
目的：探讨心肌肌钙蛋白（CTnI），肌红蛋白（MYO）和肌酸激酶同工酶（CK-MB）三者联合检测在急性心肌梗死中的应用价值。方法：将2019年3月至2020年3月在我院住院的75例急性心肌梗死患者作为观察组，体检健康者75例作为对照组。结果：两组患者的性别，年龄，并发症和家族史无显著性差异（P>0.05）；在cTnI﹑MYO和CK﹣MB方面，两组患者具有显著性差异（P<0.05）；cTnI﹑MYO和CK﹣MB三者单项检测与三者联合检测，在特异性及灵敏度方面均具备显著性差异（P<0.05）。结论：通过对心脏标志物心肌酶谱CK-MB、肌钙蛋白I、肌红蛋白的联合检测的研究，发现心脏标志物三者联合检测较其他检测方式具有较高的诊断效能，提高早期急性心机梗死患者的鉴别诊断，可采取积极救治，对降低死亡率和改善预后意义重大。
关键词
心肌梗死；检测；心肌酶
Role of three-in-one myocardial infarction in diagnosis of myocardial infarction
Abstract
Objective: To investigate the value of combined detection of cardiac troponin I (CTnI),myoglobin (MYO) and creatine kinase isoenzyme (CK-MB) in acute myocardial infarction (AMI). Methods: Seventy-five patients with acute myocardial infarction hospitalized in our hospital from March 2019 to March 2020 were selected as the observation group, and 75 healthy subjects were selected as the control group. Results: There was no significant difference in sex, age,complications and family history between the two groups (P > 0.05); there was significant difference in cTnI MYO and CK MB between the two groups (P < 0.05); there were significant differences in specificity and sensitivity between the single detection of cTnI MYO and CK MB and the combined detection of the three (P < 0.05).Conclusion: Through the study of the combined detection of cardiac markers CK-MB,troponin I and myoglobin, it is found that the combined detection of cardiac markers has higher diagnostic efficacy than other detection methods,improves the differential diagnosis of patients with early acute cardiac infarction, and can take active treatment, which is of great significance to reduce mortality and improve prognosis.
Key words
Myocardial infarction; Detection; Cardiac enzymes
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